Certified Dialysis Nurse Practice Test 2025 - Free Dialysis Nurse Practice Questions and Study Guide

Question: 1 / 400

What is nephrosclerosis primarily caused by?

Diabetes

Excessive alcohol consumption

Uncontrolled hypertension

Nephrosclerosis is primarily associated with uncontrolled hypertension because high blood pressure leads to damage in the small blood vessels of the kidneys. As blood pressure remains elevated over time, it causes changes in the kidney structure, including thickening of the vessel walls, which results in reduced blood flow and oxygen delivery to kidney tissues. This can lead to scarring (sclerosis) of kidney tissue and ultimately impair kidney function.

While other factors, such as diabetes and chronic glomerulonephritis, can also contribute to kidney damage, the direct progression of nephrosclerosis is most closely linked to the effects of hypertension. Excessive alcohol consumption can harm the kidneys but is not as direct a cause of nephrosclerosis as uncontrolled hypertension.

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Chronic glomerulonephritis

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